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  3. ABCB10

ABCB10 (ATP binding cassette subfamily B member 10)

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The Function of ABCB10

May mediate critical mitochondrial transport functions related to heme biosynthesis.

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Protein names

Recommended name:

ATP-binding cassette sub-family B member 10, mitochondrial

Short name:

M-ABC2

Alternative name(s):

ATP-binding cassette transporter 10
ABC transporter 10 protein
Mitochondrial ATP-binding cassette 2

ABCB10 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS12049351 (ABCB10) ??

Top Gene-Substance Interactions

Substances That Increase ABCB10

Substances Interaction Organism Category

Substances That Decrease ABCB10

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • CUTL1
  • CREB
  • deltaCREB
  • E2F-1
  • E2F-4
  • E2F-5
  • Lmo2

Tissue specificity:

Ubiquitous. Highly expressed in bone marrow, expressed at intermediate to high levels in skeletal muscle, small intestine, thyroid, heart, brain, placenta, liver, pancreas, prostate, testis, ovary, leukocyte, stomach, spinal cord, lymph node, trachea and adrenal gland, and low levels are found in lung, kidney, spleen, thymus and colon.

Gene Pathways:

  • Transmembrane transport of small molecules
  • ABC transporters

Molecular Function:

  • Atpase Activity, Coupled To Transmembrane Movement Of Substances
  • Atp Binding
  • Transporter Activity

Biological Processes:

  • Transmembrane Transport
  • Transport
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_05438| Abcb12| Abc-me| ABC-mitochondrial erythroid protein| ABC transporter 10 protein| AS27_01476| AS28_14004| ATP-binding cassette, sub-family B (MDR/TAP), member 10| ATP-binding cassette, subfamily B (MDR/TAP), member 10| ATP-binding cassette sub-family B member 10| ATP-binding cassette sub-family B member 10, mitochondrial| ATP-binding cassette sub-family B member 10, mitochondrial-like protein| ATP-binding cassette transporter 10| D623_10011150| EST20237| H920_04340| I79_002307| M91_02780| M959_14677| M-ABC2| MDA_GLEAN10009987| mitochondrial ATP-binding cassette 2| MTABC2| N300_11478| N301_15209| N302_14500| N303_13382| N305_10728| N306_12015| N307_04256| N308_14127| N309_08919| N310_12065| N311_01752| N312_10462| N320_00455| N321_11750| N324_09926| N325_11921| N326_03315| N327_09847| N328_11614| N330_13728| N331_07191| N332_10091| N333_08790| N334_08804| N335_03357| N336_03827| N339_10735| N341_03809| PAL_GLEAN10008084| PANDA_010501| TREES_T100013853| UY3_17812| Y1Q_012702| Y956_02942| Z169_01148| abcb10

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