The Function of ABCA12
Probable transporter involved in lipid homeostasis.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
ATP-binding cassette sub-family A member 12Alternative name(s):
ATP-binding cassette transporter 12ATP-binding cassette 12
- RS10210200 (ABCA12) ??
- RS10932600 (ABCA12) ??
- RS726070 (ABCA12) ??
- RS7560008 (ABCA12) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
Substances That Increase ABCA12
| Substances | Interaction | Organism | Category |
Substances That Decrease ABCA12
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Mainly expressed in the stomach, placenta, testis and fetal brain.
Gene Pathways:
Molecular Function:
- Receptor Binding
- Lipid Transporter Activity
- Atp Binding
- Lipid-Transporting Atpase Activity
- Apolipoprotein A-I Receptor Binding
- Atpase Activity, Coupled To Transmembrane Movement Of Substances
Biological Processes:
- Lipid Transport
- Positive Regulation Of Cholesterol Efflux
- Cellular Homeostasis
- Keratinization
- Secretion By Cell
- Phospholipid Efflux
- Ceramide Transport
- Surfactant Homeostasis
- Regulated Exocytosis
- Lung Alveolus Development
- Transmembrane Transport
- Lipid Homeostasis
- Establishment Of Skin Barrier
- Protein Localization To Plasma Membrane
- Positive Regulation Of Protein Localization To Cell Surface