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  3. ABCA12

ABCA12 (ATP binding cassette subfamily A member 12)

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The Function of ABCA12

Probable transporter involved in lipid homeostasis.

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Protein names

Recommended name:

ATP-binding cassette sub-family A member 12

Alternative name(s):

ATP-binding cassette transporter 12
ATP-binding cassette 12

ABCA12 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10210200 (ABCA12) ??
  2. RS10932600 (ABCA12) ??
  3. RS726070 (ABCA12) ??
  4. RS7560008 (ABCA12) ??

Top Gene-Substance Interactions

Substances That Increase ABCA12

Substances Interaction Organism Category

Substances That Decrease ABCA12

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-alpha

Tissue specificity:

Mainly expressed in the stomach, placenta, testis and fetal brain.

Gene Pathways:

  • Transmembrane transport of small molecules
  • ABC transporters

Molecular Function:

  • Apolipoprotein A-I Receptor Binding
  • Atpase Activity, Coupled To Transmembrane Movement Of Substances
  • Atp Binding
  • Lipid Transporter Activity
  • Lipid-Transporting Atpase Activity
  • Receptor Binding

Biological Processes:

  • Cellular Homeostasis
  • Ceramide Transport
  • Establishment Of Skin Barrier
  • Keratinization
  • Lipid Homeostasis
  • Lipid Transport
  • Lung Alveolus Development
  • Phospholipid Efflux
  • Positive Regulation Of Cholesterol Efflux
  • Positive Regulation Of Protein Localization To Cell Surface
  • Protein Localization To Plasma Membrane
  • Regulated Exocytosis
  • Secretion By Cell
  • Surfactant Homeostasis
  • Transmembrane Transport
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_12945| ABCA4| ARCI4A| ARCI4B| AS27_07227| AS28_13421| ATP-binding cassette, sub-family A (ABC1), member 12| ATP-binding cassette, subfamily A (ABC1), member 12| ATP-binding cassette, sub-family A (ABC1), member 4| ATP-binding cassette sub-family A member 12| ATP-binding cassette, sub-family A, member 12| ATP-binding cassette transporter 12| H920_20236| ICR2B| LI2| M959_07273| N300_12371| N321_02284| N333_01177| N335_13590| N340_13555| N341_02794| PAL_GLEAN10014462| TREES_T100001933| Y1Q_000146| Y956_15084| Z169_05017| abca12

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