Summary of FABP4
This gene encodes a protein that binds to fatty acids in fat cells. It plays a role in fatty acid binding, uptake, transport, and metabolism (R).
Blood levels of FABP4 is linked to severity and treatment of obstructive sleep apnea, as well as the metabolic changes as a result of the apnea (R).
0 users want this gene increased,
0 users want it decreased
The Function of FABP4
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
Protein names
Recommended name:
Fatty acid-binding protein, adipocyteShort name:
ALBPAlternative name(s):
Adipocyte lipid-binding proteinAdipocyte-type fatty acid-binding protein
A-FABP
AFABP
Fatty acid-binding protein 4
- RS1054135 (FABP4) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
FABP4 Interacts with These Diseases
Disease | Score |
Substances That Increase FABP4
Substances | Interaction | Organism | Category |
Substances That Decrease FABP4
Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
---|
Conditions with Decreased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
---|
Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Brown Fat Cell Differentiation
- Cellular Response To Lithium Ion
- Cellular Response To Tumor Necrosis Factor
- Cholesterol Homeostasis
- Cytokine Production
- Negative Regulation Of Protein Kinase Activity
- Negative Regulation Of Transcription, Dna-Templated
- Positive Regulation Of Inflammatory Response
- Triglyceride Catabolic Process
- White Fat Cell Differentiation