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ADRB3
SNP Table
| variant | genotype | frequency | risk allele |
|---|---|---|---|
| rs1193806171 | |||
| rs13306151 | |||
| rs1397593234 | |||
| rs1415543925 | |||
| rs143480096 | |||
| rs1443676189 | |||
| rs148637032 | |||
| rs150886462 | |||
| rs184077488 | |||
| rs199753604 | |||
| rs200133226 | |||
| rs200163984 | |||
| rs200277866 | |||
| rs200328265 | |||
| rs201873040 | |||
| rs36031925 | |||
| rs374271379 | |||
| rs4994 | |||
| rs4995 | |||
| rs527561891 |
Summary
The ADRB3 gene encodes adrenoreceptor B3, also called beta-adrenergic receptor 3 [R].
ADRB3 binds mainly to epinephrine. Once activated, it helps burn fat for energy and heat [R].
Variants in ADRB3 have been associated with [R, R, R, R, R]:
- Obesity
- Cholesterol & triglyceride levels
- Coronary artery disease (in Asians)
- Non-alcoholic fatty liver disease (NAFLD)
- Gestational diabetes (high blood sugar during pregnancy)
Protein names
Found in These Blog Articles
GHR Function
Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
More Information
From NCBI Gene: Obesity
From NCBI Gene: The protein encoded by this gene belongs to the family of beta adrenergic receptors, which mediate catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor is located mainly in the adipose tissue and is involved in the regulation of lipolysis and thermogenesis. [provided by RefSeq, Feb 2009] From UniProt: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. Beta-3 is involved in the regulation of lipolysis and thermogenesis.
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