Specific Granule Deficiency, also known as recurrent infection due to specific granule deficiency,is related to neutrophil-specific granule deficiency and leukemia, acute myeloid,and has symptoms including recurrent infections, hyposegmentation of neutrophil nuclei and absent neutrophil specific granules. An important gene associated with Specific Granule Deficiency is CEBPE (CCAAT/Enhancer Binding Protein Epsilon). Affiliated tissues include neutrophil, liver and monocytes, and related mousephenotypes are hematopoietic system and immune system
Disease Interacts with Genes
Disease Interacts with Substances
Processes Associated With Trait
Molecular Function Associated With Trait
Biological Processes Associated With Trait
Symptoms Associated With Trait
Selected genes are highlighted in orange, bookmarked
genes are green
- Chemical increases gene,
- Chemical decreases gene,
- Chemical increases and decreases gene simultaneosly,
No arrows - gene doesn't interact with the chemical.
- Gene should be increased/decreased most of the time and the chemical does it.
- Gene should be increased/decreased most of the time but the chemical does the opposite.