Osteolysis, Familial Expansile, also known as familial expansile osteolysis,is related to chromosome 16q22 deletion syndrome and myopia,and has symptoms including conductive hearing impairment, bone pain and thin bony cortex. An important gene associated with Osteolysis, Familial Expansile is TNFRSF11A (TNF Receptor Superfamily Member 11a), and among its related pathways are NF-kappa B signaling pathway and Rheumatoid arthritis. Affiliated tissues include bone and cortex, and related mousephenotypes are craniofacial and limbs/digits/tail
Disease Interacts with Genes
Disease Interacts with Substances
Processes Associated With Trait
Molecular Function Associated With Trait
Biological Processes Associated With Trait
Pathways Associated With Trait
Symptoms Associated With Trait
Selected genes are highlighted in orange, bookmarked
genes are green
- Chemical increases gene,
- Chemical decreases gene,
- Chemical increases and decreases gene simultaneosly,
No arrows - gene doesn't interact with the chemical.
- Gene should be increased/decreased most of the time and the chemical does it.
- Gene should be increased/decreased most of the time but the chemical does the opposite.