Platelet Disorder, Familial, with Associated Myeloid Malignancy, also known as familial platelet disorder with associated myeloid malignancy,is related to familial platelet disorder with propensity to acute myelogenous leukemia and leukemia,and has symptoms including epistaxis, bruising susceptibility and thrombocytopenia. An important gene associated with Platelet Disorder, Familial, with Associated Myeloid Malignancy is RUNX1 (Runt Related Transcription Factor 1). Affiliated tissues include myeloid, t cells and monocytes