46 Myd88 deficiency is a rare primary immunodeficiency characterized by an increased susceptibility to certain types of bacterial infections. people affected by this condition generally have abnormally frequent and life-threatening infections caused by pyogenic bacteria (such as streptococcus pneumoniae, staphylococcus aureus, and pseudomonas aeruginosa). however, their immune response to other common bacteria, viruses, fungi, and parasites is normal. myd88 deficiency is caused by changes (mutations) in the myd88 gene and is inherited in an autosomal recessive manner. management is focused on the prevention and early treatment of infections with appropriate antibiotics
Disease Interacts with Genes
Disease Interacts with Substances
Processes Associated With Trait
Molecular Function Associated With Trait
Biological Processes Associated With Trait
Pathways Associated With Trait
Symptoms Associated With Trait
Selected genes are highlighted in orange, bookmarked
genes are green
- Chemical increases gene,
- Chemical decreases gene,
- Chemical increases and decreases gene simultaneosly,
No arrows - gene doesn't interact with the chemical.
- Gene should be increased/decreased most of the time and the chemical does it.
- Gene should be increased/decreased most of the time but the chemical does the opposite.