Lig4 Syndrome, also known as lig4s,is related to dna ligase iv deficiency and nijmegen breakage syndrome,and has symptoms including microcephaly, abnormality of chromosome stability and thin vermilion border. An important gene associated with Lig4 Syndrome is LIG4 (DNA Ligase 4). Affiliated tissues include skin, bone and bone marrow
Disease Interacts with Genes
Disease Interacts with Substances
Processes Associated With Trait
Molecular Function Associated With Trait
Biological Processes Associated With Trait
Pathways Associated With Trait
Symptoms Associated With Trait
Selected genes are highlighted in orange, bookmarked
genes are green
- Chemical increases gene,
- Chemical decreases gene,
- Chemical increases and decreases gene simultaneosly,
No arrows - gene doesn't interact with the chemical.
- Gene should be increased/decreased most of the time and the chemical does it.
- Gene should be increased/decreased most of the time but the chemical does the opposite.