46 Isobutyryl-coa dehydrogenase deficiency (ibd deficiency) is an inborn error of valine (an amino acid) metabolism. the symptoms, which may not develop until later in infancy or childhood, can include failure to thrive, dilated cardiomyopathy, seizures, and anemia. ibd deficiency is caused by mutations in the acad8 gene. it is inherited in an autosomal recessive manner. treatment may include the use of l-carnitine (a safe and natural substance that helps the body's cells make energy), frequent meals, and a low-valine diet
Disease Interacts with Genes
Disease Interacts with Substances
Processes Associated With Trait
Molecular Function Associated With Trait
Biological Processes Associated With Trait
Pathways Associated With Trait
Symptoms Associated With Trait
Selected genes are highlighted in orange, bookmarked
genes are green
- Chemical increases gene,
- Chemical decreases gene,
- Chemical increases and decreases gene simultaneosly,
No arrows - gene doesn't interact with the chemical.
- Gene should be increased/decreased most of the time and the chemical does it.
- Gene should be increased/decreased most of the time but the chemical does the opposite.