46 Galloway-mowat syndrome is a rare, neurodegenerative disorder characterized by various developmental and physical abnormalities. signs and symptoms may include small head size (microcephaly); developmental delay; seizures; nephrotic syndrome; hiatal hernia; optic atrophy; movement disorders; and intellectual disability. other physical abnormalities may also be present. galloway-mowat syndrome may be caused by changes (mutations) in the wdr73 gene and is inherited in an autosomal recessive manner. other, unknown genes may also be responsible. affected children often do not survive beyond the first few years of life. treatment is aimed at the specific signs and symptoms present
Disease Interacts with Genes
Disease Interacts with Substances
Processes Associated With Trait
Molecular Function Associated With Trait
Biological Processes Associated With Trait
Selected genes are highlighted in orange, bookmarked
genes are green
- Chemical increases gene,
- Chemical decreases gene,
- Chemical increases and decreases gene simultaneosly,
No arrows - gene doesn't interact with the chemical.
- Gene should be increased/decreased most of the time and the chemical does it.
- Gene should be increased/decreased most of the time but the chemical does the opposite.