46 Factor v leiden thrombophilia is an inherited disorder that results in an increased risk of developing abnormal blood clots. factor v leiden is the name of a specific gene mutation in the f5 gene. this gene plays a critical role in the normal formation of blood clots in response to an injury. people can inherit one or two copies of the factor v leiden gene mutation. those who inherit one copy are called heterozygotes. people who inherit two copies of the mutation, one from each parent, are called homozygotes. having the factor v leiden mutation increases your risk for developing a clot in your legs called a deep venous thrombosis (dvt). it also increases your risk of developing a clot that travels through the bloodstream and lodges in the lungs, called a pulmonary embolism (pe)
Disease Interacts with Genes
Disease Interacts with Substances
Processes Associated With Trait
Molecular Function Associated With Trait
Biological Processes Associated With Trait
Pathways Associated With Trait
Selected genes are highlighted in orange, bookmarked
genes are green
- Chemical increases gene,
- Chemical decreases gene,
- Chemical increases and decreases gene simultaneosly,
No arrows - gene doesn't interact with the chemical.
- Gene should be increased/decreased most of the time and the chemical does it.
- Gene should be increased/decreased most of the time but the chemical does the opposite.