Definition
Alkaloid from fenugreek (Trigonella foenum-graecum) (Leguminosae), and very many other spp.; also present in coffee beans and many animals Trigonelline is an alkaloid with chemical formula C7H7NO2 and CAS number 535-83-1. It is found in coffee, where it may help to prevent dental caries by preventing the bacteria Streptococcus mutans from adhering to teeth.; Trigonelline is an alkaloid with chemical formula C7H7NO2. It is an inner salt formed by the addition of a methyl group to the nitrogen atom of niacin. Trigonelline is a product of the metabolism of niacin (vitamin B3) which is excreted in the urine.
Top Gene Interactions
Related Pathways
Trigonelline Health Effects
Trigonelline Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Carcinoma, Non-Small-Cell Lung | 19.68 |
|
Hyperglycemia | 13.29 |
|
Diabetes Mellitus, Experimental | 13.25 |
|
Neurotoxicity Syndromes | 13.03 |
|
Cholestasis | 12.19 |
|
Diabetic Neuropathies | 10.41 |
|
Kidney disease | 10.0 |
|
Prostatic Neoplasms | 10.0 |
|
Endometrial neoplasm | 9.38 |
|
Dermatitis, Contact | 8.73 |
|
Squamous cell carcinoma | 8.3 |
|
Diabetes Mellitus, Type 2 | 8.07 |
|
Obesity | 8.03 |
|
Fatty Liver | 7.81 |
|
Liver Diseases | 7.79 |
|
Urinary Bladder Neoplasms | 7.78 |
|
Liver Neoplasms | 7.16 |
|
Neoplasms | 7.12 |
|
Hepatocellular carcinoma | 7.01 |
|
Myocardial infarction | 6.93 |
|