Definition
A vasodilator that apparently has direct actions on blood vessels and also increases cardiac output. Tolazoline can interact to some degree with histamine, adrenergic, and cholinergic receptors, but the mechanisms of its therapeutic effects are not clear. It is used in treatment of persistent pulmonary hypertension of the newborn.
Top Gene Interactions
Tolazoline Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Abdominal obesity metabolic syndrome | 5.76 |
|
Kidney disease | 5.19 |
|
Fatty Liver, Alcoholic | 4.68 |
|
Hyperlipoproteinemias | 4.56 |
|
Encephalomyelitis, Autoimmune, Experimental | 4.28 |
|
Crohn's disease | 4.2 |
|
Hypoglycemia | 4.15 |
|
Non-alcoholic fatty liver disease | 3.99 |
|
Atopic eczema | 3.98 |
|
Hypertriglyceridemia | 3.93 |
|
Dyslipidemias | 3.9 |
|
Hyperlipidemias | 3.85 |
|
Kidney Failure, Chronic | 3.84 |
|
Kidney Tubular Necrosis, Acute | 3.8 |
|
Myocardial Reperfusion Injury | 3.75 |
|
Mammary Neoplasms, Animal | 3.66 |
|
Insulin resistance | 3.62 |
|
Reperfusion Injury | 3.62 |
|
Diabetes Mellitus, Experimental | 3.6 |
|
Diabetes Mellitus, Type 2 | 3.57 |
|