Definition
A collective name for a group of closely related lipids that contain substitutions on the 2H-1-benzopyran-6-ol nucleus and a long hydrocarbon chain of isoprenoid units. They are antioxidants by virtue of the phenolic hydrogen. Tocopherols react with the most reactive form of oxygen and protect unsaturated fatty acids from oxidation.
Tocopherols are a class of chemical compounds of which many have vitamin E activity. It is a series of organic compounds consisting of various methylated phenols. [Wikipedia]
Top Gene Interactions
Related Pathways
Tocopherols Health Effects
- 5-hydroxyeicosatetraenoic-acid inhibitor
- Allergenic
- Analgesic
- Anti aging
- Anti Alzheimeran
- Anti anginal
- Anti arteriosclerotic
- Anti arthritic
- Anti atherosclerotic
- Anti bronchitic
- Anti cancer
- Anti cariogenic
- Anti cataract
- Anti chorea
- Anti choreic
- Anti convulsant
- Anti coronary
- Anti decubitic
- Anti dementia
- Anti dermatitic
- Anti diabetic
- Anti dysmenorrheic
- Anti epitheleomic
- Anti fibrositic
- Anti glycosation
- Anti herpetic
- Anti infertility
- Anti inflammatory
- Anti ischemic
- Anti leukemic
- Anti leukotriene
- Anti lithic
- Anti lupus
- Anti maculitic
- Anti mastalgic
- Anti MD
- Anti melanomic
- Anti monosodium-glutamate
- Anti neuritic
- Anti neuropathic
- Anti nitrosaminic
- Anti ophthalmic
- Anti osteoarthritic
- Antioxidant
- Anti Parkinsonian
- Anti premenstrual syndrome
- Anti proliferant
- Anti radicular
- Anti retinopathic
- Anti rheumatic
- Anti senility
- Anti sickling
- Anti spasmodic
- Anti sterility
- Anti stroke
- Anti sunburn
- Anti syndrome-X
- Anti thalassemic
- Anti thrombotic
- Anti thromboxane-B2
- Anti toxemic
- Antitumor
- Anti ulcerogenic
- Calcium antagonist
- Cancer preventive
- Cardioprotective
- Cerebroprotective
- Circulatory stimulant
- Circulotonic
- Hepatoprotective
- Hypocholesterolemic
- Hypoglycemic
- Immunomodulator
- Immunostimulant
- Insulin-sparing
- Lipoxygenase inhibitor
- Nitric-oxide inhibitor
- Ornithine-decarboxylase inhibitor
- Cytochrome-P21 inducer
- Phospholipase-A2 inhibitor
- Protein kinase C inhibitor
- Vasodilator
- Anti aggregant
- Anti myoclonic
- Apoptotic
Tocopherols Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Hepatocellular carcinoma | 35.01 |
|
Breast carcinoma | 31.69 |
|
Prostatic Neoplasms | 23.19 |
|
Lung Neoplasms | 22.02 |
|
Colonic neoplasm | 20.37 |
|
Disease Progression | 19.05 |
|
Carcinoma, Non-Small-Cell Lung | 18.0 |
|
Colorectal cancer | 17.08 |
|
Esophageal squamous cell carcinoma | 15.11 |
|
Schizophrenia | 15.06 |
|
Stomach Neoplasms | 15.02 |
|
Carcinoma | 15.01 |
|
Adenocarcinoma | 14.92 |
|
Brain Injuries | 14.1 |
|
Hemangiosarcoma | 14.0 |
|
Reperfusion Injury | 13.82 |
|
Nerve Degeneration | 12.79 |
|
Glioma | 12.61 |
|
Cocaine dependence | 12.47 |
|
Osteosarcoma | 12.24 |
|