Definition
Description
Top Gene Interactions
Related Pathways
General Information
- Metabolism: Testosterone propionate is rapidly hydrolysed into testosterone. Testosterone is metabolized to 17-keto steroids through two different pathways. The major active metabolites are estradiol and dihydrotestosterone (DHT). Route of Elimination: About 90% of a dose of testosterone given intramuscularly is excreted in the urine as glucuronic and sulfuric acid conjugates of testosterone and its metabolites; about 6% of a dose is excreted in the feces, mostly in the unconjugated form.
- Uses/Sources: Testosterone propionate is an anabolic steroid and a short ester form of testosterone that becomes active in the body. It is often used for muscle mass building.
- Symptoms: Side effects include amnesia, anxiety, discolored hair, dizziness, dry skin, hirsutism, hostility, impaired urination, paresthesia, penis disorder, peripheral edema, sweating, and vasodilation.
Mechanism of Action
Target Name | Mechanism of Action | References |
---|---|---|
Estrogen receptor Glucocorticoid receptor Estrogen receptor beta Androgen receptor Progesterone receptor Muscarinic acetylcholine receptor M4 |
23611293 |
Testosterone Propionate Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Diabetes Mellitus, Experimental | 23.47 | |
Alzheimer's Disease | 21.42 | |
Autism | 20.15 | |
Breast carcinoma | 16.59 | |
Osteoporosis, Postmenopausal | 16.58 |
|
Parkinson's disease | 16.46 | |
Infertility, Female | 16.19 |
References/Inference Genes
|
HIV Wasting Syndrome | 15.25 |
|
Hepatocellular carcinoma | 14.52 | |
Albuminuria | 13.49 | |
Glomerulonephritis | 13.47 | |
Psoriasis | 13.33 | |
Male infertility | 13.22 | |
Heart failure | 12.66 | |
Alcohol dependence | 12.6 |
|
Stomach Neoplasms | 12.58 | |
Myocardial infarction | 12.19 | |
Prostatic Intraepithelial Neoplasia | 12.19 |
|
Mitochondrial Myopathies | 12.18 |
|
Lewy body dementia | 12.15 |
|