Definition
An HIV protease inhibitor which acts as an analog of an HIV protease cleavage site. It is a highly specific inhibitor of HIV-1 and HIV-2 proteases, and also inhibits CYTOCHROME P-450 CYP3A.
Top Gene Interactions
Related Pathways
Saquinavir Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Obesity | 31.09 |
References/Inference Genes
|
Liver Cirrhosis, Experimental | 26.65 | |
Metabolic Syndrome X | 19.91 | |
Hypertension | 19.06 |
References/Inference Genes
|
Asbestosis | 17.73 |
|
Prostatic Neoplasms | 17.53 |
References/Inference Genes
|
Heart failure | 17.41 | |
Colorectal cancer | 16.68 | |
Insulin resistance | 16.51 | |
Arthritis, Experimental | 16.47 | |
Diabetes Mellitus, Experimental | 16.3 | |
Myocardial Ischemia | 15.95 | |
Breast carcinoma | 15.85 | |
Diabetes Mellitus, Type 2 | 15.8 | |
Rheumatoid arthritis | 15.32 | |
Reperfusion Injury | 13.53 | |
Carcinoma, squamous cell of head and neck | 13.52 |
|
Atherosclerosis | 13.43 | |
Diabetic nephropathy | 13.07 | |
Kidney Failure, Chronic | 12.75 |
|