Definition
Isol. from rosemary, mint, sage, thyme, lemon balm and other plants Rosmarinic acid is an ester of caffeic acid and 3,4-dihydroxyphenyllactic acid. It is commonly found in species of the Boraginaceae and the subfamily Nepetoideae of the Lamiaceae. It is a red-orange powder that is slightly soluble in water, but well soluble is most organic solvents. Rosmarinic acid is one of the polyphenolic substances contained in culinary herbs such as perilla (Perilla frutescens L.), rosemary (Rosmarinus officinalis L.), sage (Salvia officinalis L.), mint (Mentha arvense L.), and basil (Ocimum basilicum L.). These herbs are commonly grown in the garden as kitchen herbs, and while used to add flavor in cooking, are also known to have several potent physiological effects. (PMID: 12482446, 15120569); Rosmarinic acid, C18H16O8, is a natural polyphenol antioxidant carboxylic acid found in many Lamiaceae herbs used commonly as culinary herbs such as lemon balm, rosemary, oregano, sage, thyme and peppermint. Chemically, rosmarinic acid is an ester of caffeic acid with 3,4-dihydroxyphenyl lactic acid. It is a red-orange powder that is slightly soluble in water, but well soluble in most organic solvents.
Top Gene Interactions
Related Pathways
Rosmarinic Acid Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Reperfusion Injury | 41.44 |
References/Inference Genes
|
Diabetes Mellitus, Experimental | 35.87 | |
Liver Cirrhosis, Experimental | 26.69 | |
Diabetes Mellitus, Type 2 | 25.61 | |
Colitis | 25.21 | |
Breast carcinoma | 23.9 | |
Autism | 23.48 | |
Brain Ischemia | 22.83 | |
Hypertension | 22.82 | |
Burns | 21.87 |
|
Heart failure | 21.78 | |
Heat Stroke | 20.49 |
|
Huntington Disease | 19.83 |
|
Colonic neoplasm | 19.56 | |
HIV Wasting Syndrome | 18.89 |
|
Alzheimer's Disease | 18.0 | |
Respiratory Hypersensitivity | 17.98 |
References/Inference Genes
|
Stomach Neoplasms | 17.75 | |
Myocardial infarction | 17.4 | |
Atherosclerosis | 17.28 |
References/Inference Genes
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