Top Gene Interactions
- Uses/Sources: Used as an adjunctive therapy to induce thrombolysis in patients suffering acute myocardial infarction.
- Route of Exposure: Rapidly absorbed after oral administration (30-60 min)
Mechanism of Action
|Target Name||Mechanism of Action||References|
Thromboxane A2 synthase
Thromboxane A2 receptor
|Ridogrel inhibits thromboxane A2 synthase and also blocks the thromboxane A2/prostaglandin endoperoxide receptors. Thromboxane synthetase produces thromboxane in platelets. Thromboxane is a vasoconstrictor and facilitates the clumping of platelets. Therefore by inhibiting the production and promotion of thromboxane, thrombolysis is reduced.||