Definition
An acridine derivative formerly widely used as an antimalarial but superseded by chloroquine in recent years. It has also been used as an anthelmintic and in the treatment of giardiasis and malignant effusions. It is used in cell biological experiments as an inhibitor of phospholipase A2.
Top Gene Interactions
Related Pathways
Quinacrine Interacts with Diseases
| Disease | Inference Score | References/Inference Genes |
| Prostatic Neoplasms | 12.66 | |
| Diabetes Mellitus, Experimental | 11.73 | |
| Esophageal Neoplasms | 9.75 |
|
| Male infertility | 9.68 |
|
| Carotid Artery Diseases | 9.34 |
|
| Hypertension, Essential | 9.21 |
|
| Breast carcinoma | 9.12 | |
| Hepatocellular carcinoma | 9.01 | |
| Carcinoma, Non-Small-Cell Lung | 8.9 |
References/Inference Genes
|
| Adrenocortical Carcinoma | 8.77 |
|
| Lymphoma, T-Cell, Cutaneous | 8.51 |
|
| Cardiac hypertrophy | 8.09 | |
| Carcinoma, squamous cell of head and neck | 7.78 |
|
| Adenocarcinoma | 7.72 |
References/Inference Genes
|
| Infertility, Female | 7.29 |
|
| Osteosarcoma | 7.12 |
|
| Arsenic Poisoning | 7.04 |
|
| Chronic obstructive pulmonary disease | 6.94 |
|
| Non-alcoholic fatty liver disease | 6.81 |
|
| ORNITHINE TRANSCARBAMYLASE DEFICIENCY, HYPERAMMONEMIA DUE TO | 6.62 |
|