Definition
Constit. of Punica granatum (pomegranate) Punicalagin is the major tannin component of Terminalia catappa and have been characterized to possess antioxidative and anti-genotoxic activities. ; T. catappa has been a popular folk medicine for preventing hepatoma and treating hepatitis in Taiwan; the leaves contain many hydrolyzable tannins. Although the leaves of T. catappa have been claimed to be effective in preventing hepatoma, the mechanism of its chemopreventive effect remains to be elucidated, and their effects on reactive oxygen species (ROS) mediated carcinogenesis are still unclear. (PMID: 16242868)
Top Gene Interactions
Related Pathways
Punicalagin Health Effects
Punicalagin Interacts with Diseases
| Disease | Inference Score | References/Inference Genes |
| Arthritis, Experimental | 9.76 |
|
| Osteoarthritis | 9.64 |
|
| Craniofacial Abnormalities | 9.21 |
|
| Achondrogenesis type 2 | 7.26 |
|
| Epiphyseal Dysplasia, Multiple, with Myopia and Conductive Deafness | 7.26 |
|
| Kniest dysplasia | 7.26 |
|
| Legg-Calve-Perthes Disease | 7.26 |
|
| Osteoarthritis with Mild Chondrodysplasia | 7.26 |
|
| Platyspondylic Lethal Skeletal Dysplasia, Torrance Type | 7.26 |
|
| Spondyloepiphyseal dysplasia, congenita | 7.26 |
|
| Stickler syndrome, type 1 | 7.26 |
|
| Stickler Syndrome, Type I, Nonsyndromic Ocular | 7.26 |
|
| Strudwick syndrome | 7.26 |
|
| Spondyloepimetaphyseal Dysplasia, Missouri Type | 7.25 |
|
| Inflammation | 7.06 |
|
| Hyaloideoretinal degeneration of Wagner | 6.92 |
|
| Megaepiphyseal dwarfism | 6.92 |
|
| OTOSPONDYLOMEGAEPIPHYSEAL DYSPLASIA | 6.92 |
|
| Spondylometaphyseal dysplasia, Kozlowski type | 6.92 |
|
| Chondrosarcoma | 6.71 |
|