Definition
A tetracyclic compound with antidepressant effects. It may cause drowsiness and hematological problems. Its mechanism of therapeutic action is not well understood, although it apparently blocks alpha-adrenergic, histamine H1, and some types of serotonin receptors.
Top Gene Interactions
Related Pathways
Mianserin Interacts with Diseases
| Disease | Inference Score | References/Inference Genes |
| Drug-induced liver injury | 11.02 |
|
| Hypertension | 10.78 |
|
| Liver Cirrhosis, Experimental | 10.44 |
|
| Breast carcinoma | 8.92 |
|
| Kidney disease | 7.99 | |
| Inflammation | 7.66 |
|
| Edema | 6.07 |
|
| Hepatocellular carcinoma | 5.99 |
|
| Hyperalgesia | 5.75 | |
| Drug-Related Side Effects and Adverse Reactions | 5.71 |
|
| Acute kidney injury | 5.55 |
|
| Nerve Degeneration | 5.48 |
|
| Bradycardia | 5.36 |
|
| LONG QT SYNDROME 13 | 5.22 |
|
| Cocaine dependence | 5.11 |
|
| Hypotension | 5.06 |
References/Inference Genes
|
| Memory Disorders | 5.03 |
|
| Substance Withdrawal Syndrome | 5.0 |
|
| VESICOURETERAL REFLUX 3 | 4.95 |
|
| Fever | 4.74 |
|