Definition
An HIV protease inhibitor used in a fixed-dose combination with RITONAVIR. It is also an inhibitor of CYTOCHROME P-450 CYP3A.
Top Gene Interactions
Related Pathways
Lopinavir Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Pulmonary Fibrosis | 28.51 | |
Brain Ischemia | 27.37 | |
Arthritis, Experimental | 24.59 | |
Crohn's disease | 23.06 |
|
Osteoporosis, Postmenopausal | 21.55 |
|
Reperfusion Injury | 21.54 | |
Rheumatoid arthritis | 20.41 | |
Glomerulonephritis | 19.75 |
|
Kidney Failure, Chronic | 19.35 |
References/Inference Genes
|
HIV Wasting Syndrome | 18.78 |
|
Myocardial Ischemia | 18.55 | |
Inflammation | 18.14 |
References/Inference Genes
|
Allergy | 18.08 |
|
Metabolic Syndrome X | 17.3 | |
Atherosclerosis | 17.09 | |
Breast carcinoma | 16.62 | |
Diabetes Mellitus, Type 2 | 16.6 | |
Status Epilepticus | 16.58 | |
Hypertension | 15.8 | |
Mitochondrial Myopathies | 15.69 |
|