Definition
Very widespread in the plant world, e.g. in Brassicaceae, Apocynaceae, Dilleniaceae, Ranunculaceae, Leguminosae, etc. Found esp. in broccoli, capers, chives, kale, garden cress, fennel, lovage, dill weed and tarragon [CCD] Kaempferol is a natural flavonol, a type of flavonoid. Many glycosides of kaempferol, such as kaempferitrin and astragalin, have been isolated as natural products from plants. Kaempferol consumption in tea and broccoli has been associated with reduced risk of heart disease. [Wikipedia]
Description
Kaempferol is a natural flavonoid which has been isolated from Delphinium, Witch-hazel, grapefruit, and other plant sources. Kaempferol is a yellow crystalline solid with a melting point of 276-278 degree centigrade. It is slightly soluble in water, and well soluble in hot ethanol and diethyl ether.
Top Gene Interactions
Related Pathways
Kaempferol Health Effects
- 11beta-hydroxysteroid-dehydrogenase inhibitor
- 5-lipoxygenase inhibitor
- Anti aflatoxin
- Anti allergic
- Anti cancer
- Anti fertility
- Anti gingivitic
- Anti herpetic
- Anti histaminic
- Anti implantation
- Anti inflammatory
- Anti leukemic
- Anti lymphocytic
- Antioxidant
- Anti periodontic
- Anti plaque
- Anti radicular
- Anti septic
- Anti serotonin
- Anti spasmodic
- Anti staphylococcic
- Antitumor
- Anti ulcer
- Anti viral
- Aromatase inhibitor
- Cancer preventive
- Carcinogenic
- Choleretic
- Copper chelator
- Cyclooxygenase-2 inhibitor
- Cyclooxygenase inhibitor
- Cytotoxic
- Diaphoretic
- Diuretic
- Fungicide
- Hepatoprotective
- HIV-reverse-transcriptase inhibitor
- Hypotensive
- ICAM-1 inhibitor
- INOS inhibitor
- Iodothyronine-deiodinase inhibitor
- JNK inhibitor
- Lipoxygenase inhibitor
- Monoamine-oxidase inhibitor
- Natriuretic
- Neuroprotective
- Nitric-oxide inhibitor
- Platelet aggregation factor inhibitor
- Pesticide
- Protisticide
- Quinone-reductase inducer
- Teratologic
- TNF-alpha inhibitor
- Topoisomerase-II inhibitor
- Topoisomerase-I inhibitor
- Tyrosinase inhibitor
- Utero trophic
- Vasodilator
- Aldose reductase inhibitor
- Anti aggregant
- Anti bacterial
- Anti mutagenic
- Antitumor promoter
- Apoptotic
- CAMP-phosphodiesterase inhibitor
- Estrogenic
- Inotropic
- Mutagenic
General Information
- Uses/Sources: Kaempferol is a natural flavonoid which has been isolated from Delphinium, Witch-hazel, grapefruit, and other plant sources.
Mechanism of Action
Target Name | Mechanism of Action | References |
---|---|---|
Estrogen receptor Estrogen receptor beta Progesterone receptor UDP-glucuronosyltransferase 3A1 |
10592235 23611293 |