IRINOTECAN

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Irinotecan Interacts with Diseases

Disease	Inference Score	References/Inference Genes
Liver Cirrhosis, Experimental	86.37	References/Inference Genes References Inference genes 16552806 16496349 15745444 16097045 18251166 12389079 17127702 26435214 16116963 15996030 16642209 15591519 17072980 12667390 17347453 17963606 16085334 16539848 21163135 16688825 15362042 16953842 12632514 15095483 16126171 25380136 26806094 16609999 18054572 A2M ABCB1 ABCC2 ACAT1 ACHE ADA ADD3 AGT ALB ALDH1A1 ANXA2 ATF3 BCR BIRC3 C7 CCNB2 CD163 CD36 CDK1 CDKN1A CDKN3 COL6A1 CTGF CXCL12 FGF2 FOS GJA1 GSTA3 HELLS ID2 IFNG IGF1 IL10 IL18 IL1B KNG1 LBH MALAT1 MGMT MMP9 MT1A NDRG1 NFKBIA NID1 PCK1 PLAT PRKCB PRKCD PRLR PTPRD RAB31 RAMP1 RARRES1 RECK RELA TNF TSPAN8 UBD
Breast carcinoma	80.55	References/Inference Genes References Inference genes 11967536 10930538 19655245 19896266 20562527 26192916 16495393 22311042 22302033 16818634 23063927 19617202 19238537 25221644 16137437 16298037 19552798 16865596 16596621 26124351 15496535 9309585 23001124 18511948 16091755 19756960 15601643 20197467 12839951 18521742 17520698 20332317 16978400 16950593 12006526 18297428 14672398 21638049 20154269 16234514 22204715 15341671 23621182 12690581 25688741 18925433 20948315 11237771 11970740 19234134 23289900 19436038 19385967 17659439 18483385 17922014 23535733 12655533 18398872 22572619 25330770 17965603 16954440 25078270 16968874 16446318 17450141 16682728 23867902 25358515 11583189 17516992 18507500 22267197 19446661 11248153 17614302 10897039 16322251 18819904 11222871 18768436 17293864 21501481 24014025 18086299 15122511 26229107 19020767 15994142 15970926 18840765 16799634 17388661 15802278 20135347 20354179 12517783 16904380 19435922 19801490 21463514 16723031 20941507 19075277 15581045 ABCB1 ABCC1 ABCG2 ACHE ADAMTS1 AREG ATM BAX BCL2 BIRC2 BIRC5 CASP8 CDKN2A CENPF CHEK1 CHEK2 COL7A1 CXCL12 CXCL8 CYP3A4 DPYD EGFR ENO1 EP300 ERBB2 ETS2 FN1 FOS FOXA1 FTO GZMB H2AFX HMMR HRG IFNG IGF1 IGFBP5 IL1B IL6 JUN KRT5 MDM2 MMP9 NCOA1 NDRG1 NFKBIA NQO1 NRIP1 PTPRD RB1 RELA SERPINB5 SOD2 TFRC THBS1 TNF TNFSF10 TOP2A TP53 TYMS
Prostatic Neoplasms	76.18	References/Inference Genes References Inference genes 17507624 16984552 15341671 19074884 16775185 17115417 11222871 12237244 17875776 17804715 16606632 24586243 22564066 15877079 22610119 16516039 17606477 12727815 21209944 17202838 21946351 26098866 17363566 19011039 25415046 17914592 20356562 16552752 23996089 16733517 12533788 12644816 25970160 17199135 18306354 19240160 17363613 26457646 26005866 17502119 17196815 18174250 16368536 20875869 17465268 23315858 15999119 16465378 16284379 18829485 15672864 15496535 25320179 17136230 17999153 25735316 17718901 16434975 16998812 19208208 17785557 17909013 15598783 17542986 18264096 21716162 15302576 17013881 15378487 17636462 17196171 24763052 15583422 17688413 17003774 17646272 12592389 ABCC4 ACHE APC ATF3 ATM BAX BCL2 CASP9 CDKN1A CHEK2 CREBBP CTBP2 CXCL12 CXCL8 CYP2A6 CYP3A4 CYP3A5 EGFR EGR1 ERBB2 FASLG FGF2 FOXA1 GDF15 GGT1 GJA1 GPX3 HBG1 IGF1 IL10 IL18 IL2 IL6 MAPK3 MDM2 MLH1 MMP9 MPO MSR1 NCOA1 NDRG1 NQO1 NR3C1 PAWR PPP3CA PRKDC RAD23B RLIM RUNX1 SLC31A1 SOD2 TGFA TNFSF10 TOP2A TP53 TRAF1 TYMS USO1 ZFP36L2
Colorectal cancer	59.35	References/Inference Genes References Inference genes 22294766 7705931 18829568 15172127 12907644 16364925 15706408 23431386 18716850 16111806 18676755 24836286 17943475 20593958 21278247 16943523 15222106 12690581 15814641 18718023 17892325 15500737 17949449 21946351 19020767 21544799 16110022 18949393 16524972 17683511 18607850 18998757 23977225 15386371 18497967 17611699 17450141 21892161 12645814 21967605 17273769 19309276 19509152 10853026 18084292 17047489 20065508 17116713 17575224 16963246 18507500 21291235 16141798 18483336 16331619 ABCB1 ABCC1 ABCC2 ABCC4 ABCG2 APC BCL2 BIRC5 BOLL CASP8 CFTR CHEK2 COL7A1 CXCL8 CYP2A6 DPYD EGFR EP300 GATA4 GREM1 MLH1 MSH2 NQO1 PRKCB PROM1 PTPRD SERPINB5 SLC19A1 SOD2 TCF7L2 TFRC TNF TNFSF10 TP53 TXNRD1 TYMP TYMS VTI1A
Hepatocellular carcinoma	58.97	References/Inference Genes References Inference genes 21472284 17191126 19731237 18230555 15289866 23392203 18477611 21822264 27022031 15565109 12029619 18760346 16799960 19363144 11509945 14961299 20214788 20512989 16284949 17615358 16086872 16767786 14578863 19514085 25822088 17510421 18019677 22675488 17326159 20818158 22634756 8033108 22022477 20514400 10629087 9029167 17363595 22488367 19919837 21147110 12432545 15509519 20084675 A2M ABCB1 ACACA ADAMTS1 APC ARID2 ATM BCL2L1 BIRC5 CASP8 CCR1 CDKN2A CXCL12 CXCL8 DPYD EGFR ENO1 FOS GDF15 HGFAC HTATIP2 IL6 JUN MLXIPL MMP9 MPO MT1A NFKBIA PCK1 PTK2 RB1 SMOC SOD2 STAT1 TGFA THEM4 TNF TNFSF10 TP53 TYMS UBD
Stomach Neoplasms	58.13	References/Inference Genes References Inference genes 21133646 18505590 22484628 22414649 18652704 15723263 21364592 15940630 17963294 19424620 17355264 26098866 19020767 15993841 14503839 26401016 15837757 17450141 12115524 17089033 25279216 15378696 19584167 15095271 22037551 21532492 16134180 1733439 21173787 24816253 21364753 10853026 14647439 15640503 22042947 15201584 17003101 23593346 15492468 16367923 ALB APC AREG ATM AURKB BCL2L1 BIRC2 BIRC5 CASP8 CDKN1A CDKN2A CHEK2 CXCL8 CYP2A6 DLC1 DPYD EGFR ENO1 ERBB2 ERCC1 GKN1 GREM1 HBEGF IL1B IL6 JUN MAPK1 MAPK3 PRKAA1 PRKCB PTPRG RARRES1 SMOC SOD2 TGFA TNF TP53 TYMP TYMS ZBTB20
Carcinoma, Non-Small-Cell Lung	57.69	References/Inference Genes References Inference genes 15341671 21777763 15956251 19375815 11731445 21479364 21789004 21933749 17290066 21553054 22751098 21791641 15496427 9865924 18337602 19027488 20471133 21440325 20627363 22948846 16382892 21782507 22286583 23912706 16862215 26482881 22919003 21268124 19941079 19358281 22617245 22787409 16230376 24467950 17233834 21904575 17043644 21807637 23435014 24688052 22787412 17094902 21336183 21478906 ABCB1 ADAMTS1 APC AREG ATF3 BIRC5 CASP8 CDKN2A CXCL8 EGFR ENO1 ERCC1 FASLG FGF9 IL10 MDM2 MMP9 NDRG1 NQO1 OSMR PHLDA2 PSAT1 RB1 RECK SDC4 SOD2 TGFA TP53
Colonic neoplasm	53.28	References/Inference Genes References Inference genes 18652704 16284371 11222871 12079509 17192441 18987561 26192916 20876807 12842827 17443689 25200834 15059925 15355913 15705887 17510416 12034317 19147571 14569062 8608549 12628520 7846077 17075118 16224667 25043185 18192902 21383188 25279216 10866311 10223192 20715105 17404573 16609021 18283038 10383901 15993848 15725655 26335331 21188121 19105824 19028472 A2M APC ATP7A BAX BCL2 BIRC5 CDKN1A DPYD EGFR ERBB2 IFNG IL1B JUN LTF MLH1 MMP9 NFKB1 PLCB1 PROM1 RECK RELA SERPINB5 SLC19A1 SOD2 TCF7L2 TNF TNFSF10 TP53 TYMP TYMS
Rheumatoid arthritis	47.13	References/Inference Genes References Inference genes 23897011 12566094 20080907 8391952 22104130 22450443 2001072 18794853 26001728 20453841 22286218 17379860 19898480 23143596 15292528 20453842 12833524 20008919 24313545 16368150 21190368 19192274 ABCB1 ABCC2 ABCC4 ABCG2 CCR6 CDK6 CTGF CXCL8 DDIT4 ENO1 FASLG FKBP5 GATA3 HLA-DRB1 IFNG IL10 IL18 IL1B IL6 MPO PTK2 PTPN22 RBPJ RUNX1 SOD2 STAT1 TNF TNFRSF14 TRAF1
Lung Neoplasms	42.25	References/Inference Genes References Inference genes 18927287 26372664 16289808 11872642 10441482 17114358 16176798 15981204 22369883 18298334 12466968 2305558 11884234 26192916 11798837 26132489 24880342 21552421 19336973 12376484 19020767 18281538 20727180 20135361 12115568 17325666 17311802 12111688 16926031 18337602 20716630 17450141 20934974 11241319 16904380 23692979 7614408 16108013 20464547 17902193 15166089 19180532 23523951 12083368 17549345 16410370 18625569 20682992 19903766 14587096 12214673 21541241 18508827 16007126 12483526 A2M ADA ANXA2 APC BCL2L1 BIRC5 CASP8 CDKN1A CDKN2A CES1 CHEK2 COL6A1 CTGF CYP2A6 DPYD EGFR ERBB2 FAS FGF9 FOS GJA1 GPX3 IFNG IL10 IL1B IL2 IL6 JUN MAPK1 MAPK3 MCL1 MPO TFRC TNF TP53 TYMS
Endometriosis	42.24	References/Inference Genes References Inference genes 23284138 21063030 25446850 20864642 22138541 ABCC4 ANKH AREG DUSP1 EGFR FKBP5 FOS GPX3 HBEGF HS3ST3B1 IGF1 IL15 ITGA2 KLF9 LTF NCOA1 NR3C1 NR3C2 PRLR RBPJ RGS4
Squamous cell carcinoma	38.38	References/Inference Genes References Inference genes 22948846 26372664 12543247 16280240 25125259 12942316 15274141 21401805 25194279 26432044 15956251 22042947 11237771 24224046 18572023 27158780 25199511 17418620 17979968 ANXA2 AREG ATM BIRC5 CDKN2A CREBBP CXCL8 EGFR ENO1 EP300 IL6 KNSTRN MAPK1 MAPK3 MMP9 MT1A PRKDC PTK2 RASA1 SOD2 TP53 TYMS
Reperfusion Injury	37.73	References/Inference Genes References Inference genes 17032661 12024109 8869312 23743330 23075401 16971220 7635938 19917352 7922267 18258783 16968891 15829914 20302854 15449323 8215636 9472885 12468449 16526316 16682413 17112405 18460982 21940958 19673871 19193722 12865660 10706834 10594344 19058328 23875703 20863214 AGT BCL2 CASP3 CASP8 CD36 CDKN1A CXCL8 EGR1 FGF2 FOS HBEGF IL10 IL1B IL6 JUN MMP9 MPO PLAT RELA SOD2 THBS1 TNF
Mammary Neoplasms, Experimental	37.19	References/Inference Genes References Inference genes 17584969 21080969 21252285 8603490 15217511 2523869 12376462 16316942 14522882 12606953 14999141 25221644 15528971 22767648 24809783 23964924 21283680 ABCG2 CDK6 EGFR ENO1 ERBB2 FN1 GATA3 GGT1 IGF1 IL10 INSIG1 KRT5 MMP9 NCOA1 PRLR PTK2 RASA1 RB1 SGK1 SOD2 TFF1 TNFSF10
Brain Ischemia	36.87	References/Inference Genes References Inference genes 14986460 21037505 9236716 17086147 17903870 20212195 20536612 16763187 16809570 19429140 15737438 12511774 7477192 15829914 15060315 17394460 9566367 19095966 9259745 11108748 12221155 11940547 15756928 11756504 15017018 17525387 17901229 9400355 16126134 15087567 9633741 10572812 20123226 20488584 19417757 9479658 18628779 ADD3 ALB CASP3 CASP9 EGR1 IL17A IL18 IL1B IL6 JUN MAPK1 MAPK3 MMP9 MPO NFKB1 NFKBIA PLAT RB1 RELA SOD2 TNF TNFRSF1A TP53
Neoplasm Metastasis	35.34	References/Inference Genes References Inference genes 18398872 16984552 18930813 11103787 21937440 22580338 23431386 21312072 20957146 12538496 27137931 12015757 21209944 17949449 19487542 23996089 17717427 12748951 19514085 17611699 21942447 24244343 23743303 21080969 16475674 23867902 20801905 17369752 15659795 15867226 17233834 22972152 17575224 17003774 8032535 17105418 ABCB1 ABCC4 CXCL12 DPYD EGFR ERBB2 ERCC1 GDF15 IGF1 IL18 IL2 IL6 MALAT1 MAPK1 MAPK3 MLH1 MMP9 NCOA1 NDRG1 RB1 RECK SERPINB5 SLC39A4 SOD2 SP1 TNF TNFSF10 TP53 TYMP
Glioblastoma multiforme	35.18	References/Inference Genes References Inference genes 20127710 18829568 19204207 7661930 15341671 22162573 16356833 26651356 18679414 21877938 23917401 12811834 17099729 26455392 20131314 19718438 23582323 16598420 20534551 7719933 APC CDK6 CXCL8 EGFR FN1 H2AFX IL1B IL2 MGMT MMP9 NDRG1 PROM1 PTK2 RECK RUNX1 TNFSF10
Urinary Bladder Neoplasms	33.04	References/Inference Genes References Inference genes 26039340 15987713 18930813 24121791 11103787 22015448 15906354 21760912 22929185 21822268 22747749 12926068 11723127 1949363 16565513 16904380 9070496 23523951 8631603 15841086 3495671 14729580 1674182 9610789 12376482 18713828 18640142 12973940 19415693 AS3MT ATM BIRC3 CDKN1A CDKN2A CREBBP CXCL8 CYP4B1 EGFR EP300 FAS IGF1 IGFBP5 IL2 MPO MT1A NQO1 POR RB1 SLC19A1 SOD2 TFRC TNF TP53 TYMP
Diabetes Mellitus, Experimental	32.09	References/Inference Genes References Inference genes 15831366 20363216 22191573 12123627 23458895 20388520 23792339 21340626 19478208 17177138 16959961 20654064 24632065 15855331 16123366 24513509 21963884 22138235 18829990 12198386 12193562 23090186 AGT ATF3 BAX BCL2 BCL2L1 CASP3 FAS IFNG IGF1 IL1B IL6 MMP9 MPO NQO1 PCK1 PRKCA PRKCD RELA SOD2 TNF TNFRSF1A TP53
Arthritis, Juvenile	31.76	References/Inference Genes References Inference genes 19565504 AREG DUSP1 DUSP2 EGR1 ETV6 FOS HBEGF JUN KLF4 MAPK1 SMAD3 TCF7L2 TFPI THBS1 TNFAIP6

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Irinotecan Interacts with Diseases

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