Definition
Occurs widely in animals and plants. Component of nucleic acids (CCD) Guanine (G) is one of the four main nucleobases found in the nucleic acids DNA and RNA, the others being adenine, cytosine, and thymine (uracil in RNA). In DNA, guanine is paired with cytosine. With the formula C5H5N5O, guanine is a derivative of purine, consisting of a fused pyrimidine-imidazole ring system with conjugated double bonds. Being unsaturated, the bicyclic molecule is planar. The guanine nucleoside is called guanosine. (Wikipedia)
Top Gene Interactions
Related Pathways
Guanine Health Effects
Guanine Interacts with Diseases
| Disease | Inference Score | References/Inference Genes |
| Glioblastoma multiforme | 8.82 |
|
| Micronuclei, Chromosome-Defective | 8.48 |
|
| Colorectal cancer | 7.58 |
|
| Purine Nucleoside Phosphorylase Deficiency | 7.19 |
|
| Xanthinuria, Type I | 6.7 |
|
| Lipodystrophy | 6.08 |
|
| Jaw Abnormalities | 6.04 |
|
| Hypogonadism | 5.52 |
|
| Deafness | 5.24 |
|
| Abnormalities, Multiple | 5.07 |
|
| Arsenic Poisoning | 4.96 |
|
| Endometrial neoplasm | 4.93 |
|
| Carcinoma, squamous cell of head and neck | 4.84 |
|
| Recurrence | 4.75 |
|
| Osteoporosis | 4.74 |
|
| Brain Neoplasms | 4.68 |
|
| Esophageal squamous cell carcinoma | 4.56 |
|
| Infarction, Middle Cerebral Artery | 4.55 |
|
| Mouth Neoplasms | 4.55 |
|
| Major Depression | 4.35 |
|