Definition

An oral hypoglycemic agent which is rapidly absorbed and completely metabolized.

Description

Glipizide is only found in individuals that have used or taken this drug. It is an oral hypoglycemic agent which is rapidly absorbed and completely metabolized. [PubChem]Sulfonylureas likely bind to ATP-sensitive potassium-channel receptors on the pancreatic cell surface, reducing potassium conductance and causing depolarization of the membrane. Depolarization stimulates calcium ion influx through voltage-sensitive calcium channels, raising intracellular concentrations of calcium ions, which induces the secretion, or exocytosis, of insulin.

Top Gene Interactions

Related Pathways

General Information

Toxicity

Mechanism of Action

Glipizide Interacts with Diseases

Glipizide Interacts with Genes