Definition
Widespread isoflavone found in soy beans (Glycine max), red clover (Trifolium pratense and chick peas (Cicer arietinum). Potential nutriceutical Formononetin are abundant in vegetables. It is a phyto-oestrogen that is a polyphenolic non-steroidal plant compound with oestrogen-like biological activity (PMID: 16108819). It can be the source of considerable estrogenic activity (http://www.herbalchem.net/Intermediate.htm).
Top Gene Interactions
Related Pathways
Formononetin Health Effects
Formononetin Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Breast carcinoma | 39.85 |
References/Inference Genes
|
Colorectal cancer | 34.5 | |
Prostatic Neoplasms | 26.54 | |
Myocardial Reperfusion Injury | 26.36 | |
Alzheimer's Disease | 25.49 | |
Adenocarcinoma | 22.48 | |
Acute kidney injury | 21.38 | |
Brain Ischemia | 21.3 | |
Reperfusion Injury | 20.25 | |
Diabetes Mellitus, Experimental | 19.99 | |
Diabetes Mellitus, Type 2 | 19.55 | |
Hepatocellular carcinoma | 19.25 | |
Esophageal Neoplasms | 18.48 | |
Male infertility | 18.4 | |
Carcinoma, squamous cell of head and neck | 17.93 |
|
Drug-Related Side Effects and Adverse Reactions | 17.63 | |
Dermatitis, Contact | 17.46 |
|
Hypertension | 17.29 | |
Stomach Neoplasms | 16.24 | |
Chronic obstructive pulmonary disease | 16.06 |