Definition
A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion.
Famotidine is a histamine H2-receptor antagonist that inhibits stomach acid production, and is commonly used in the treatment of peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD/GORD). It is commonly marketed by Merck under the trade names Pepcidine and Pepcid. [HMDB]
Top Gene Interactions
Related Pathways
Famotidine Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Reperfusion Injury | 47.68 |
References/Inference Genes
|
Radiation Injuries, Experimental | 34.29 |
References/Inference Genes
|
Hepatitis, Autoimmune | 28.76 |
|
Ulcerative colitis | 28.74 | |
Lung Neoplasms | 28.56 | |
Brain Ischemia | 27.19 | |
Entamoebiasis | 26.94 |
|
Prostatic Neoplasms | 26.06 |
References/Inference Genes
|
Brain Injuries | 25.91 | |
Pulmonary Fibrosis | 25.09 | |
Diabetes Mellitus, Experimental | 25.03 | |
Leishmaniasis, Cutaneous | 24.77 | |
Autism | 24.37 | |
Colitis | 23.34 | |
Neoplasm Metastasis | 23.26 | |
Visceral leishmaniasis | 23.13 | |
Glomerulonephritis | 22.97 | |
Arthritis, Experimental | 22.85 | |
Oral Submucous Fibrosis | 22.79 |
|
Wounds and Injuries | 21.74 |
References/Inference Genes
|