Used as a food additive [EAFUS]


Pentaerythritol tetranitrate (PETN), also known as PENT, PENTA, TEN, corpent, penthrite is the nitrate ester of pentaerythritol, and is structurally very similar to nitroglycerin. PETN is best known as an explosive. It is one of the most powerful high explosives known. PETN mixed with a plasticizer forms a plastic explosive. It is also used as a vasodilator drug to treat certain heart conditions, such as for management of angina. PETN works by releasing the signaling gas nitric oxide in the body. The heart medicine Lentonitrat is nearly pure PETN. Monitoring of oral usage of the drug by patients can be performed by determination of plasma levels of several of its hydrolysis products, pentaerythritol dinitrate, pentaerythritol mononitrate and pentaerythritol, in plasma using gas chromatography-mass spectrometry.

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