Top Gene Interactions
Estrone Health Effects
- Metabolism: Hepatic. Half Life: 19 hours
- Uses/Sources: For management of perimenopausal and postmenopausal symptoms.
- Symptoms: Symptoms of overdose include nausea and vomiting. Estrogen related side effects include nausea, breast tenderness, fluid retention and edema, headaches and/or migraines, chloasma and poor contact lens fit. Estrogen hormone deficiency is associated with breakthrough bleeding, hypomenorrhea, irritability, depression and menopausal symptoms. Withdrawal bleeds may occur in females.
- Route of Exposure: 43%
Mechanism of Action
|Target Name||Mechanism of Action||References|
Estrogen receptor beta
Nuclear receptor subfamily 1 group I member 2