Definition
A class I anti-arrhythmic agent (one that interferes directly with the depolarization of the cardiac membrane and thus serves as a membrane-stabilizing agent) with a depressant action on the heart similar to that of guanidine. It also possesses some anticholinergic and local anesthetic properties.
Top Gene Interactions
Related Pathways
Disopyramide Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Lipidoses | 7.18 |
|
Brugada Syndrome 8 | 6.6 |
|
Sick Sinus Syndrome 2, Autosomal Dominant | 6.6 |
|
Obesity | 6.09 |
|
Osteosarcoma | 6.04 |
|
Farber Lipogranulomatosis | 5.91 |
|
Short QT Syndrome 1 | 5.77 |
|
Long Qt Syndrome 2 | 5.08 |
|
Torsades de pointes | 4.94 |
|
Jaundice, Neonatal | 4.73 |
|
Colonic neoplasm | 4.32 |
|
Atrial fibrillation | 4.09 |
|
Barrett's esophagus | 3.94 |
|
Hypophosphatemia | 3.72 |
|
Muscular Atrophy | 3.71 |
|
Metabolic Syndrome X | 3.3 |
|
Infertility, Female | 3.29 |
|
Liver Cirrhosis, Experimental | 3.29 |
|
Hepatitis C | 3.28 |
|
Long QT Syndrome | 3.24 |
|