Definition
A semisynthetic macrolide antibiotic derived from ERYTHROMYCIN that is active against a variety of microorganisms. It can inhibit PROTEIN SYNTHESIS in BACTERIA by reversibly binding to the 50S ribosomal subunits. This inhibits the translocation of aminoacyl transfer-RNA and prevents peptide chain elongation.
Top Gene Interactions
Related Pathways
Clarithromycin Interacts with Diseases
| Disease | Inference Score | References/Inference Genes |
| Leishmaniasis, Cutaneous | 14.81 |
|
| HIV Wasting Syndrome | 14.52 |
|
| Visceral leishmaniasis | 13.76 | |
| Mesothelioma, Malignant | 12.58 |
|
| Hemolytic-Uremic Syndrome | 12.12 |
|
| Glomerulonephritis | 12.11 | |
| Pleural Diseases | 12.09 |
|
| Arthritis, Experimental | 12.05 | |
| Oral Submucous Fibrosis | 12.05 |
|
| Mitochondrial Myopathies | 11.46 |
|
| Acute coronary syndrome | 11.41 |
|
| Pulmonary Fibrosis | 11.24 | |
| Burns | 11.09 |
|
| Chronic obstructive pulmonary disease | 10.88 |
References/Inference Genes
|
| Cachexia | 10.62 |
|
| Allergy | 10.53 | |
| Brain Ischemia | 10.48 | |
| Leishmaniasis | 10.44 |
|
| Polymyositis | 10.39 |
|
| Colonic neoplasm | 10.26 |