Definition
A glucoside-derived SODIUM-GLUCOSE TRANSPORTER 2 inhibitor that stimulates urinary excretion of glucose by suppressing renal glucose reabsorption. It is used to manage BLOOD GLUCOSE levels in patients with TYPE 2 DIABETES.
Top Gene Interactions
Related Pathways
Canagliflozin Interacts with Diseases
| Disease | Inference Score | References/Inference Genes |
| Hyperostosis | 6.77 |
|
| Bone Diseases, Endocrine | 6.43 |
|
| Hypoparathyroidism familial isolated | 6.43 |
|
| Ige Responsiveness, Atopic | 6.07 |
|
| Rickets | 5.84 |
|
| Fractures, Bone | 5.77 |
|
| Hyperphosphatemia | 5.71 |
|
| Hyperparathyroidism, Secondary | 5.65 |
|
| Hypertension | 5.53 |
|
| Osteoporosis, Postmenopausal | 5.49 |
|
| Hypercalciuria | 5.41 |
|
| Bone Resorption | 5.21 |
|
| Uremia | 5.06 |
|
| Hypocalcemia | 5.04 |
|
| Focal segmental glomerulosclerosis | 4.93 |
|
| Hypercalcemia | 4.81 |
|
| Osteoporosis | 4.67 |
|
| Anemia | 4.26 |
|
| Proteinuria | 4.22 |
|
| Heart failure | 4.11 |
|