Definition
Constit. of Corylus avellana (filbert) and Vicia faba Betulin is an abundant naturally occurring triterpene. It is commonly isolated from the bark of birch trees and forms up to 30% of the dry weight of the extractive. The purpose of the compound in the bark is not known. It can be converted to betulinic acid (the alcohol group replaced by a carboxylic acid group), which is biologically more active than betulin itself.; Chemically, betulin is a triterpenoid of lupane structure. It has a pentacyclic ring structure, and hydroxyl groups in positions C3 and C28.
Top Gene Interactions
Related Pathways
Birch Bark Extract (Betulin) Health Effects
Birch Bark Extract (Betulin) Interacts with Diseases
Disease | Inference Score | References/Inference Genes |
Alcoholic liver cirrhosis | 32.92 |
|
Diabetes Mellitus, Experimental | 26.38 |
|
Oral Submucous Fibrosis | 26.29 |
|
Liver Cirrhosis, Experimental | 21.99 |
|
Calcinosis | 21.06 |
|
Neoplasms, Experimental | 19.74 |
|
Pleural Diseases | 18.65 |
|
Pulmonary Fibrosis | 17.49 |
|
Hepatitis, Autoimmune | 16.59 |
|
Liver Cirrhosis | 15.72 |
|
Crohn's disease | 14.84 |
|
Neoplasm Invasiveness | 14.72 |
|
Myocardial infarction | 13.32 |
|
Entamoebiasis | 12.53 |
|
Abortion, Spontaneous | 12.44 |
|
Thoracic aortic aneurysm | 12.3 |
|
Copper-Overload Cirrhosis | 12.11 |
|
Inflammation | 11.7 |
|
Pulmonary Emphysema | 11.44 |
|
Aids | 11.35 |
|