Definition
Isol. from Citrus aurantium (Seville orange) and bael fruit (Aegle marmelos) Auraptene is a natural bioactive monoterpene coumarin ether. It was first isolated from members of the genus Citrus. Auraptene has shown a remarkable effect in the prevention of degenerative diseases. Many studies have reported the effect of auraptene as a chemopreventative agent against cancers of liver, skin, tongue, esophagus, and colon in rodent models. The effect in humans is not yet known.
Top Gene Interactions
Related Pathways
Aurapten Health Effects
Aurapten Interacts with Diseases
| Disease | Inference Score | References/Inference Genes |
| Breast carcinoma | 23.9 | |
| Hepatocellular carcinoma | 21.07 | |
| Prostatic Neoplasms | 18.06 | |
| Liver Cirrhosis, Experimental | 16.25 | |
| Arthritis, Juvenile | 14.89 |
|
| Dermatitis, Contact | 14.28 |
|
| Hemangiosarcoma | 13.67 |
|
| Osteosarcoma | 12.43 |
|
| Colonic neoplasm | 11.78 | |
| Colorectal cancer | 11.69 | |
| Kidney Neoplasms | 10.76 |
|
| Stomach Neoplasms | 10.65 | |
| Coronary artery disease | 10.5 |
References/Inference Genes
|
| Intestinal Polyps | 10.23 |
|
| Adrenal Gland Neoplasms | 9.97 |
|
| Carcinoma, Non-Small-Cell Lung | 9.83 |
References/Inference Genes
|
| Pancreatic carcinoma | 9.61 |
References/Inference Genes
|
| Brain Injuries | 9.48 |
References/Inference Genes
|
| Adrenocortical Carcinoma | 9.47 |
|
| Carcinoma, Pancreatic Ductal | 9.45 |
|