Definition
An antipsychotic agent that is structurally related to piperazines and quinolones. It is a partial agonist of SEROTONIN RECEPTOR, 5-HT1A and DOPAMINE D2 RECEPTORS, where it also functions as a post-synaptic antagonist, and an antagonist of SEROTONIN RECEPTOR, 5-HT2A.
Top Gene Interactions
Related Pathways
Aripiprazole Interacts with Diseases
| Disease | Inference Score | References/Inference Genes |
| Cocaine dependence | 22.49 |
References/Inference Genes
|
| Schizophrenia | 17.27 | |
| Autism | 13.46 | |
| Basal Ganglia Diseases | 12.73 | |
| Amphetamine-Related Disorders | 12.63 | |
| Alcohol dependence | 12.16 |
References/Inference Genes
|
| Endometriosis | 8.64 |
References/Inference Genes
|
| Attention deficit hyperactivity disorder | 8.18 |
|
| Sezary Syndrome | 7.75 |
|
| Drug dependence | 7.64 | |
| Substance Withdrawal Syndrome | 7.51 | |
| Hypogonadism | 7.41 |
|
| Weight Gain | 7.26 |
References/Inference Genes
|
| Pituitary Neoplasms | 7.18 |
|
| Obesity | 7.13 | |
| Pheochromocytoma | 7.13 |
|
| Arthritis, Juvenile | 6.96 |
|
| Huntington Disease | 6.87 |
|
| Cognitive impairment | 6.71 |
References/Inference Genes
|
| Obsessive-compulsive disorder | 6.61 |
|