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Fear & Anxiety: 3 Genes To Look At

min read

Essential Takeaways

Fear and anxiety are a result of biochemical changes and there are numerous genes and biological sources that can create and make them worse.
OXTR encodes the oxytocin receptor, which communicates closely with parts of the brain involved in fear. Some genetic variants may increase anxiety by making you more sensitive to “signs of threat”.
That said, scientists have found there are specific diet, supplement and lifestyle changes that can change the way your genes function and improve your anxiety and fear response.


Get health recommendations based on your own DNA, labs & lifestyle.


Get health recommendations based on your own DNA, labs & lifestyle.

What if you could go through life without fear and anxiety?

How would your life look?

Oftentimes, these feelings seep into every aspect of your life and stop you in your tracks.

But did you know that this feeling fear and anxiety are a result of biochemical changes?

Not only that, but there’s many different genes and biological sources that create and make it worse.

When I was suffering from anxiety and depression, I would use Dr. Google and come across so many articles on how to “fix your anxiety” and I would literally try them all.

I was taking lemon balm, chamomile, passionflower and theanine because they were some of the best supplements for anxiety – but they didn’t help me at all.

You name it, I tried it (and wasted tons of money doing so.) I would literally have to take every single supplement I could get my hands on, but even then it wasn’t always clear what was working and what wasn’t. Sometimes you have to take them for an extended period of time to see if something works.

Anxiety response is affected by so many things, like oxytocin, GABA, BDNF, glutamate, serotonin, and cortisol.

So how do you discover what you’re susceptible to?

The answer lies in your genes.

It wasn’t until I started looking at my genes that my life completely changed. I managed to pinpoint exactly what my body needed, and found the supplements that effectively worked on me. My anxiety completely went away, and this process helped me save money as well.

Not only did this work for me, but I use the same approach to help my partners and friends.

By looking at your genes, you can discover diet, supplement, and lifestyle changes that can decrease your anxiety, improve your mood, and completely change your life.

Oxytocin, OXTR Gene and Your Amygdala

When you feel threatened and afraid, a part of your brain – called the amygdala – automatically activates the fight-or-flight response. Oxytocin (or the love hormone) decreases the sensitivity your amygdala has to signs of threat.

If you carry the negative variant of the OXTR gene, your oxytocin levels will decrease. This means you will be more sensitive to smaller “signs of threat,” which can cause anxiety to occur on things like a short social interaction.

If you do carry the negative variant, there’s a specific natural, plant supplement that can increase your OXTR gene activity, improve your oxytocin, and decrease your anxiety!

PITX2 Gene and GABA

The PITX2 gene enables the production of GABA, which is an extremely important neurotransmitter that produces a calming effect when it attaches to proteins in your brain.

The negative variant actually decreases GABA production, which is a hallmark in plenty of different anxiety disorders.

There’s a specific tea that targets the bad gene variant by helping to balance the GABA levels in your brain.

BDNF Gene and Cortisol

The BDNF gene creates BDNF (Brain-derived neurotrophic factor), which prevents the excess release of the stress hormone cortisol.

The bad variant of this gene actually has a number of negative effects. Decreased BDNF causes an increase in cortisol, which results in higher anxiety levels. On top of that, excess cortisol damages the hippocampus, which results in more stress-related hormones running rampant in the brain.

That’s why it’s extremely important to understand what variant you carry, so that you can implement changes that will counteract any negative effects.

How To Check All Of Your Anxiety Genes

We often neglect taking care of our mental health. But If you haven’t made it a priority, now is the perfect time.

With our scientific research, genetic data, and AI technology, there’s an easy way to check ALL of the genes related to your anxiety, and find out what the most important changes are for your body.

With the SelfDecode Anxiety DNA report, we look at the 3 genes listed above, along with over 800,000 genetic variants related to anxiety.

Plus, it’s so easy to start seeing results right away. We give you a prioritized list of personalized diet, lifestyle, and supplement recommendations that will work better than anything else you’ve tried because they’re based on your body.

These aren’t generic recommendations, they are specific to your genes.

AUTHOR: Joe Cohen, SelfDecode CEO

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